Mutational Bias in Penguin Microsatellite DNA
نویسندگان
چکیده
منابع مشابه
Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability.
Microsatellite instability (MSI) is observed in a subset of endometrial cancers (ECs) and is attributed to defects in mismatch repair. Mismatch repair deficiency allows for accumulation of mutations in the coding repeats of key target genes, which may be involved in the initiation and progression of MSI+ EC. We examined genes implicated in DNA repair pathways in 38 MSI-high (MSI-H), 10 MSI-low,...
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ژورنال
عنوان ژورنال: Journal of Heredity
سال: 2005
ISSN: 1465-7333,0022-1503
DOI: 10.1093/jhered/esi070